CRC Tier 1 - Determining why mutations of the metabolic enzyme isocitrate dehydrogenase cause leukemias and brain cancers

H Leighton Grimes

Developing Novel STAT5 Protein Inhibitors for Treatment of Leukemias

Leukaemia

Hematology and hematologic malignancies Pathology

Michael R Green

Identification and Characterization of Genes that Suppress BCR-ABL+ Leukemia

Leukaemia

Hematology and hematologic malignancies Pathology

Robert C Castellino

Mechanisms of PPM1D in Medulloblastoma Tumorigenesis and Invasion

Brain, nervous system

Dana Pe'Er

Integrative Cancer Genomics: Drivers, Pathways and Drugs

Brain, nervous system

Stephen V Desiderio

Temporal and Spatial Control of V(D)J Recombination

Leukaemia

Pathology Hematology and hematologic malignancies Pediatric oncology or childhood cancer

Inanc Birol

High throughput analysis of RNA-seq reads to characterize alternative polyadenylation in myeloid malignancy

Leukaemia

Robert G Roeder

Transcriptional Regulatory Mechanisms in B Cell Development and Leukemogenesis

Leukaemia

Pediatric oncology or childhood cancer Hematology and hematologic malignancies Pathology

Monica J Justice

The Pluripotency Regulator Prdm14 Initiates Cancer by Epigenetic Mechanisms

Leukaemia

Pathology Hematology and hematologic malignancies

Robert J Wechsler-Reya

Cellular and Genetic Basis of Anaplastic Medulloblastoma

Brain, nervous system

Pediatric oncology or childhood cancer